[Met5, Lys6,7] a-Neo-Endorphin (1-7) CAS NO.80237-40-7

[Met5, Lys6,7] a-Neo-Endorphin (1-7) CAS NO.80237-40-7

[Met5, Lys6,7] a-Neo-Endorphin (1-7) CAS NO.80237-40-7

[Met5, Lys6,7] a-Neo-Endorphin (1-7) CAS NO.80237-40-7

[Met5, Lys6,7] a-Neo-Endorphin (1-7) CAS NO.80237-40-7

[Met5, Lys6,7] α-Neo-Endorphin (1-7) is a synthetic heptapeptide analog derived from the endogenous opioid α-Neoendorphin, featuring key amino acid substitutions at positions 5, 6, and 7 (Met, Lys, Lys). This modification is designed to enhance peptide stability and alter receptor interaction profiles compared to the native sequence. It is primarily utilized in biochemical re찾다 as a tool compound for investigating opioid receptor signaling, structure-activity relationships (SAR), and pain modulation pathways, strictly for re찾다 purposes.


TECHNICAL SPECIFICATIONS


Item
Specification
제품 이름
[Met5, Lys6,7] a-Neo-Endorphin (1-7)
CAS NO.
80237-40-7
Appearance
White to off-white lyophilized powder
Molecular Formula
C₃₉H₅₉N₉O₉S
Molecular Weight
849.0g/mol
Purity (RP-HPLC)
≥98% 
Solubility

Soluble in 1M acetic acid, DMSO, or deionized water

Endotoxin
≤1 EU/mg 
Biological Activity
Potent agonist for mu and kappa opioid receptors; modulates pain perception and neurotransmitter release
Storage Conditions
Store at -20°C, protected from light and moisture
Stock 위치
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

The peptide retains the conserved N-terminal Tyr-Gly-Gly-Phe motif essential for opioid receptor engagement. It functions as a ligand for G protein-coupled opioid receptors (primarily μ and κ subtypes), activating inhibitory G proteins upon binding. This interaction triggers a cascade that reduces adenylate cyclase activity and cAMP 제품ion, leading to neuronal hyperpolarization and inhibition of neurotransmitter release, which underlies its potential modulatory effects on pain perception and neuronal excitability.

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2.제품 INDICATIONS

This 제품 is indicated for Re찾다 Use Only (RUO), targeting academic institutions, pharmaceutical R&D departments, and biotech re찾다ers focused on neuropharmacology. It is applied in in vitro receptor binding assays, functional cell-based studies, and animal model experiments to elucidate the role of opioid systems in analgesia, addiction, and neuropsychiatric disorders. It is not intended for diagnostic or therapeutic use in humans.

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3.CLINICAL EFFICACY OF 제품

While not approved for clinical use, experimental data from preclinical studies suggest that this analog exhibits bioactive properties characteristic of opioid peptides, including potential analgesic and behavioral effects in animal models. Its efficacy is primarily demonstrated in re찾다 settings for validating receptor targets and screening novel therapeutic candidates, with no established human clinical trial data.

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4.자격증

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide 제품, adhering strictly to quality standards and obtaining internation모두y recognized 인증s.


우리 제품ion partners 모두 employ GMP-compliant 제품ion systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of 제품 comes with complete documentation, including a 자격증 of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and re찾다-grade peptide 제품 to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging 해결책 to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the 제품.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the 제품ion and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The 회사 invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA 인증s, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality 제품 and superior services.


We focus on the re찾다 and development and supply of high-quality chemical 제품, strictly adhering to international standards and quality systems. 우리 제품s are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific re찾다, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


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If you have any 제품 requirements, please 보내다 an 이메일 to:support@huanqiukeji9.com;whatsapp:85244969439

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