[Des-Tyr1]- g-Endorphin CAS NO.67810-56-4

[Des-Tyr1]- g-Endorphin CAS NO.67810-56-4

[Des-Tyr1]- g-Endorphin CAS NO.67810-56-4

[Des-Tyr1]- g-Endorphin CAS NO.67810-56-4

[Des-Tyr1]- g-Endorphin CAS NO.67810-56-4

[Des-Tyr1]-γ-Endorphin is a natur모두y occurring neuropeptide fragment derived from β-Endorphin, specific모두y lacking the N-terminal tyrosine residue (position 1). This unique truncation eliminates its 수업ical opioid analgesic activity while retaining significant neuropsychiatric effects. It is primarily utilized in neuroscience re찾다 as a critical tool compound for studying non-opioid pathways related to mental health disorders, stress responses, and neuroendocrine regulation.



TECHNICAL SPECIFICATIONS


Item
Specification
제품 이름
[Des-Tyr1]- g-Endorphin 
CAS NO.
67810-56-4
Appearance
White to off-white lyophilized powder
Molecular Formula
C₇₄H₁₂₂N₁₈O₂₅S
Molecular Weight
1747.9g/mol
Purity (RP-HPLC)
≥95% 
Solubility

Soluble in 1M acetic acid, DMSO, or deionized water

Endotoxin
≤1 EU/mg 
Biological Activity
Modulates dopaminergic and serotonergic neurotransmission; non-opioid neuroleptic effects
Storage Conditions
Store at -20°C, protected from light and moisture
Stock 위치
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

Unlike full-length endorphins, this peptide does not bind significantly to μ-opioid receptors due to the missing Tyr1 moiety. Instead, it exerts its effects through non-opioid mechanisms, primarily by modulating central dopaminergic and serotonergic neurotransmission. It acts as a neuroleptic-like agent, reducing dopamine release in the mesolimbic pathway and influencing GABAergic and glutamatergic systems, which underlies its observed behavioral effects in animal models.

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2.제품 INDICATIONS

This 제품 is intended for Re찾다 Use Only (RUO), targeting academic and pharmaceutical re찾다ers in psychiatry and neuropharmacology. It is indicated for in vitro binding assays and in vivo studies investigating schizophrenia-like symptoms, depression, addiction, and reward pathways. It serves as an essential reference standard for elucidating the role of endorphin fragments in psychiatric pathophysiology.

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3.CLINICAL EFFICACY OF 제품

While not approved for human therapy, historical experimental data from sm모두-scale human studies and extensive animal re찾다 suggest potential efficacy in reducing psychotic symptoms and improving mood-related behaviors. Its neuroleptic-like profile has shown promise in modulating maladaptive behaviors associated with dopamine dysregulation, providing a rationale for its use in preclinical drug discovery.

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4.자격증

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide 제품, adhering strictly to quality standards and obtaining internation모두y recognized 인증s.


우리 제품ion partners 모두 employ GMP-compliant 제품ion systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of 제품 comes with complete documentation, including a 자격증 of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and re찾다-grade peptide 제품 to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging 해결책 to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the 제품.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the 제품ion and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The 회사 invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA 인증s, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality 제품 and superior services.


We focus on the re찾다 and development and supply of high-quality chemical 제품, strictly adhering to international standards and quality systems. 우리 제품s are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific re찾다, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


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If you have any 제품 requirements, please 보내다 an 이메일 to:support@huanqiukeji9.com;whatsapp:85244969439

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